Chrons Disease Symptom
Endoscopy image of colon showing serpiginous ulcer, easily seen in Crohn's disease. Many people with Crohn's disease symptoms years before the diagnosis. Usually the onset is between 15 and 30 years, but can occur at any age. Due to the nature of "irregular" gastrointestinal disease and depth of tissue involvement can be the initial symptoms are more unstable than typical ulcerative colitis. People with Crohn's disease flare of chronic recurrent symptoms and blame the remission period.
Abdominal pain can be the first symptom of Crohn's disease. A "often accompanied by diarrhea, especially in those who underwent surgery. Diarrhea may be more or less bloody. The nature of the diarrhea in Crohn's disease depends on the part of the small intestine and colon involved. Ileiti usually leads to large volumes of watery stool. Colitis can result in less stool volume, but with a higher frequency. Fecal consistency may range from solid to weak. In severe cases, an individual more than 20 days and bowel discharge need to wake up at night to defecate. Blood in stool is less frequent in Crohn's disease compared with ulcerative colitis, but may be discovered in connection with Crohn's colitis. Intestinal draining blood are usually transient and may be bright red or dark. In severe colitis, Crohn's disease, it may be heavy bleeding. Bloating and swelling can be added to intestinal problems.
Symptoms caused by stenosis are also common intestinal Crohn's disease. Abdominal pain is often acute in areas that narrowing of the intestine. In the context of severe stenosis, vomiting and nausea may indicate the beginning of small bowel obstruction. Although the correlation is higher in relation to ulcerative colitis, Crohn's disease may also be associated with primary sclerosing cholangitis, a type of inflammation of the bile ducts.
Problems in the perianal area may be important in Crohn's disease. Itching or pain around the "anus may indicate inflammation, fistulization or abscess around. Perianal skin tags are common. Faecal incontinence may accompany diseases of perianal Crohn's disease. At the opposite end of the digestive tract may be affected by non-healing wounds mouth (aphthous ulcers). Rarely the esophagus and stomach may be involved in disease. If disabled, can cause symptoms such as difficulty in swallowing (dysphagia), upper abdominal pain and vomiting.
Crohn's disease, as well as many other chronic inflammatory diseases, can cause a number of systemic symptoms. In children, growth failure is common. Many of them are diagnosed with the disease due to their inability to maintain proper growth. Up to 30% of children with this disease with growth retardation. Fever may be present, even more to 38.5 ˚ C is rare, if there are no complications such as abscess. Elderly, Crohn's disease manifest as weight loss is usually related to decreased food intake, because patients with symptoms of intestinal Crohn's disease often feel better when not eating. People with this disease in a large part of the small intestine may also have malabsorption of carbohydrates or fats, which can further exacerbate weight loss.
Nutritional deficiency due to reduced intake of anorexia and self-imposed determines steatorrhea, megaloblastic or microcytic anemia, hypoprotidemia, edema, bone demineralization, dehydration and hypokalemia.
Chrons Disease Extraintestinal
In addition to systemic and gastrointestinal involvement of Crohn's disease can also affect many other organs. Inflammation of the eye, known as uveitis, can cause severe pain, especially when the eye is exposed to light (photophobia). Inflammation may also involve the white of the eye (sclera), a condition called episcleritis. Both episcleritis uveitis, which can lead to blindness if left untreated.
Crohn's disease is associated with the type of rheumatologic disease known as seronegative spondyloarthropathy. It is characterized by inflammation of one or more joints (arthritis) or muscle insertions (enthesitis). Arthritis can affect larger joints such as knees or shoulders, or may include only the small joints of hands and feet. Arthritis can also involve the spine, leading to ankylosing spondylitis if the entire structure is, or simply sacroiliitis if only the lower spine is involved. Symptoms of arthritis include pain, warmth, swelling, stiffness and loss of joint mobility or function.
Crohn's disease may also affect the skin, blood and endocrine system. Type of skin exposure, "erythema nodosum, shown as red nodules which usually appear on the shins. Erythema nodosum is due to inflammation of the subcutaneous base, and is characterized by septal panniculitis. Another skin lesion, pyoderma gangrenosum, is typically characterized by painful ulcerating node. Crohn's disease also increases the risk of blood clots, swelling and pain in the legs, and can be a symptom of deep vein thrombosis, while difficulty breathing may be due to pulmonary embolism. "Hemolytic anemia is an autoimmune disease in which the immune system attacks the red blood cells, which is common Crohn's disease and can cause fatigue, pallor, and other symptoms common in "anemia. Clubs, deformities at the ends of the fingers may be due to illness. Finally, Crohn's disease causes of osteoporosis and bone loss. People with osteoporosis are at increased risk of bone fractures .
Crohn's disease can cause complications, neurological (as reported in 15% of patients). The most common are seizures, stroke, myopathy, peripheral neuropathy, headache and depression.
Influence of disease may also suffer from granulomatous cheilitis and other forms of orofacial granulomatosis.
Chrons Disease Complication
Crohn's disease can lead to several complications in the intestines, including obstruction, development of fistulae and abscesses. Generally the block valve, or adhesions which narrow the lumen, blocking the passage of intestinal contents. Fistulae may develop between two loops bowel, between bowel and bladder, between the intestine and vagina, and between the intestine and skin. Abscesses may occur in the abdomen or in the perianal area.
Crohn's disease also increases the risk of cancer in the area of inflammation. For example, people with Crohn's disease involving the small bowel are at increased risk of colon cancer. Likewise, people with Crohn's colitis have a relative risk of 5.6 for developing colon cancer. Screening for colorectal cancer with colonoscopy is designed for those with Crohn's colitis for at least eight years.
Individuals with Crohn's disease are at risk of malnutrition for many reasons, including reduced food intake and absorption. The risk increases after small bowel resection. These individuals may require oral supplements to increase their calorie intake, or in severe cases, parenteral nutrition, total (TPN). Most people with moderate to severe Crohn's disease turn to for help dietitian in nutrition.
Crohn's disease can be problematic during pregnancy and some medications can cause side effects on the fetus or mother. Consultation with the obstetrician and gastroenterologist about Crohn's disease and all medicines, it can be assumed, it may take preventive measures. In some cases, during pregnancy may lead to remission of the disease. Some drugs can affect sperm count, or information, may adversely affect fertility in men.
Other complications of the disease may be "infected Iris and" anorexia.